These are the serial scans of a 37-year-old woman G3, P2 performed at 35 and 37 weeks of gestation. There is no significant past medical or obstetric history.

Dilated loops of bowel were seen in all the scans. No other fetal anomaly was observed. A C-section was performed and the baby was admitted in the neonatal unit. Radiographic studies showed bowel dilatation. The baby was operated on day three, and surgery confirmed the presence of meconium ileus. A jejunostomy was performed.

Postnatal DNA testing found the fetus to be homozygous for the Y 122 X (cystic fibrosis) mutation. The chloride- sweat test was positive. The baby also had exocrine pancreatic insufficiency (low levels of elastase and chymotrypsin).

A final diagnosis of cystic fibrosis was made.